According to the Centers for Disease Control and Prevention, one in six deaths from cardiovascular diseases was attributed to stroke in 2020. Annually, about 795,000 people in the United States suffer a stroke, with roughly 610,000 of these being first-time strokes. Stroke is a leading cause of severe long-term disability in adults and significantly reduces the mobility of over half of the survivors aged 65 and above.

Hyperbaric therapy has shown promising results in both preventing and treating strokes through various mechanisms. It can precondition the brain by stimulating angiogenesis, which creates new blood pathways in the brain, potentially reducing the risk of stroke. Furthermore, hyperbaric therapy has been beneficial for patients after a stroke. It aids in restoring blood flow and functionality to the brain areas affected by compromised circulation (penumbra), primarily through the enhanced delivery of oxygen which supports healing. Studies have demonstrated the effectiveness of this treatment even years after the initial stroke incident.